1
Table of contents
4
Preface
5
A letter to Our patrons

Endocrinology

8
Cigarette smoking and hormone balance in women: New evidence in the anti-smoking campaign
Murray D. Meek
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Cardiac Surgery

12
Coronary artery bypass surgery: historical overview and future directions
Salvatore Privitera
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Medical Imaging

18
Cerebral vascular reactivity evaluation by BOLD fMRI
Gregory Krolczyk
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News and Views

22
Forum: How should physicians interpret the new guidelines on breast self-exam?
Ann M. Stewart
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26
In the Literature
Tania Samanta
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29
Law and ethics in medicine: the ethics of embryonic stem cell research
Anil J. Misir
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31
Separating Mary and Jodie: an application of medical ethics
Sarah Marks and Selene Etches
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33
Prolific scientist profiles: The 2001 Gairdner Foundation Awards
Marie L. Cappello
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35
Prolific scientist profiles: An interview with Dr. Henry Friesen, 2001 Wightman Award winner
Marie L. Cappello
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38
Back to basics VIII: Cancer chemotherapy: The role of pharmacological agents in the management of hematological malignancies
Paolo Mazzotta, Agnes Kwasnicka and George J. Kutas
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Clinicopathological Correlation

46
A relatively common childhood cancer
Guangming Han and Pedram Kazemian
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Quick Diagnosis

52
Sushmita Pamidi, Karoon C. Danayan, Andrea Johston and Anatoli Freiman
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Technology Review

56
Microarrays - Tools for the genomics age
Alia Qureshi Emili
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Morning Report

61
Accounting for polyuria
Michelle Porepa, Xerxes Punthakee and Jordan Weinstein
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Historical Review

65
Therapeutic use of leeches: from the "Annelids" of medicine
Robert Adam and Peter Zakrzewski
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Economics and Health Policy

68
MRI supply in Canada: What are the issues?
Pavi S. Kundhal, S. Chatterjee and Kiran K. Kundhal
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Complementary Medicine

70
The increasing popularity of complementary and alternative medicine in Canada
Rahim Hirji and Peter Zakrewski
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Aikins Award

73
History of the W.T. Aikins Awards
74
W.T. Aikins Winners 1985-2001
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Book Reviews

75
Biohazard
Nicholas B. J. Tan
76
The politics of passion: Norman Bethune's writing and art
Tyler Rouse
77
What your doctor really thinks: Diagnosing the Doctor-Patient relationship
Christina R. Tunzi
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Front cover illustration by Betty Lee
Department of Biomedical Communications, University of Toronto